Thématique 1 : Infection par le VIH, traitement et observance au traitement anti-rétroviral
Mots clés (3 maximum) : observance, traitement anti-rétroviral, VIH
Responsable scientifique : Pr Renaud VERDON, verdon-r@chu-caen.fr et Dr Jean-Jacques PARIENTI , parienti-jj@chu-caen.fr
Encadrement de master ou thèse non
1. Gras G, Geffray L, Parienti JJ, Yazdanpanah Y, Etienne M, Schmit JL, Verdon R; G4 study group. Late diagnosis and subsequent survival among HIV-infected truck drivers in the northwest of France: a retrospective study. AIDS. 2009 Jul 17;23(11):1440-2.
2- Parienti JJ, Bangsberg DR, Verdon R, Gardner EM.Better adherence with once-daily antiretroviral regimens: a meta-analysis. Clin Infect Dis. 2009 Feb 15;48(4):484-8.
3- Parienti JJ, Das-Douglas M, Massari V, Guzman D, Deeks SG, Verdon R, Bangsberg DR. Not all missed doses are the same: sustained NNRTI treatment interruptions predict HIV rebound at low-to-moderate adherence levels. PLoS ONE. 2008 Jul 30;3(7):e2783.
4- Parienti JJ, Massari V, Reliquet V, Chaillot F, Le Moal G, Arvieux C, Vabret A, Verdon R; POSOVIR Study Group. Effect of twice-daily nevirapine on adherence in HIV-1-infected patients: a randomized controlled study. AIDS. 2007 Oct 18;21(16):2217-22.
5- Parienti JJ, Massari V, Rey D, Poubeau P, Verdon R; SIROCCO study team.Efavirenz to nevirapine switch in HIV-1-infected patients with dyslipidemia: a randomized, controlled study. Clin Infect Dis. 2007 Jul 15;45(2):263-6. Epub 2007 Jun 6.
6- Dargere S, Parienti JJ, Verdon R. Treatment resistance after sequential interruption of a non-nucleoside reverse transcriptase inhibitor-based regimen. AIDS. 2007 Apr 23;21(7):879-80. No abstract available.
7- Parienti JJ, Verdon R, Massari V.Methodological standards in non-inferiority AIDS trials: moving from adherence to compliance. BMC Med Res Methodol. 2006 Sep 20;6:46.
8- Parienti JJ, Massari V, Descamps D, Vabret A, Bouvet E, Larouzé B, Verdon R. Predictors of virologic failure and resistance in HIV-infected patients treated with nevirapine- or efavirenz-based antiretroviral therapy. Clin Infect Dis. 2004 May 1;38(9):1311-6. Epub 2004 Apr 14.
Thématique 1 : Entérocoques
Mots clés (3 maximum) : facteurs de pathogénicité ; résistance aux antibiotiques ; typage
Responsable scientifique : Roland Leclercq Mail : leclercq-r@chu-caen.fr
Intitulé de l’équipe : EA2128 Interactions hôte et microorganismes des épithéliums
Encadrement de master ou thèse oui
Thématique 2 : Résistance aux antibiotiques chez les bactéries à Gram-positif
Mots clés (3 maximum) : streptocoques ; staphylocoques ; gènes de résistance
Responsable scientifique : cattoir-v@chu-caen.fr
Intitulé de l’équipe : EA2128 Interactions hôte et microorganismes des épithéliums
Encadrement de master ou thèse oui
1. Charbonneau P, Parienti JJ, Thibon P, Ramakers M, Daubin C, du Cheyron D, Lebouvier G, Le Coutour X, Leclercq R; French Fluoroquinolone Free (3F) Study Group. Fluoroquinolone use and methicillin-resistant Staphylococcus aureus isolation rates in hospitalized patients: a quasi experimental study. Clin Infect Dis. 2006;42:778-784.
2. Depardieu F, Podglajen I, Leclercq R, Collatz E, Courvalin P. Modes and modulations of antibiotic resistance gene expression. Clin Microbiol Rev. 2007;20:79-114.
3. Achard A, Leclercq R. Characterization of a small mobilizable transposon, MTnSag1, in Streptococcus agalactiae. J Bacteriol. 2007;189:4328-4331.
4. Arsène S, Leclercq R. Role of a qnr-like gene in the intrinsic resistance of Enterococcus faecalis to fluoroquinolones. Antimicrob Agents Chemother. 2007;51:3254-3258.
5. Achard A, Guérin-Faublée V, Pichereau V, Villers C, Leclercq R. Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. Antimicrob Agents Chemother. 2008;52:2767-2770.
6. Cattoir V, Poirel L, Nordmann P. Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. Antimicrob Agents Chemother. 2008;52:3801-4.
7. Petinaki E, Guérin-Faublée V, Pichereau V, Villers C, Achard A, Malbruny B, Leclercq R. Lincomycin resistance gene lnu(D) in Streptococcus uberis. Antimicrob Agents Chemother. 2008;52:626-630
8. Boumghar-Bourtchai L, Mariani-Kurkdjian P, Bingen E, Filliol I, Dhalluin A, Ifrane SA, Weill FX, Leclercq R. Macrolide-resistant Shigella sonnei. Emerg Infect Dis. 2008;14:1297-9.
9. Phuc Nguyen MC, Woerther PL, Bouvet M, Andremont A, Leclercq R, Canu A. Escherichia coli as reservoir for macrolide resistance genes. Emerg Infect Dis. 2009;15:1648-50.
10. Boumghar-Bourtchaï L, Dhalluin A, Malbruny B, Galopin S, Leclercq R. Influence of recombination on development of mutational resistance to linezolid in Enterococcus faecalis JH2-2. Antimicrob Agents Chemother. 2009;53:4007-9.
