Nom du chef de service : Pr E. BINGEN
Thématique 1 : Physiopathologie et facteurs de virulence des infections extra-intestinales à E. coli en Pédiatrie
Mots clés (3 maximum) : E. coli, facteurs de virulence, méningite néonatale.
Nom et adresse e-mail du responsable scientifique : edouard.bingen@rdb.aphp.fr
Intitulé de l’équipe : EA 3105
Encadrement de master ou thèse oui
Thématique 2 : Facteurs de virulence chez Streptococcus pyogenes
Mots clés (3 maximum) : S. pyogenes, emm1, enfant
Nom et adresse e-mail du responsable scientifique : edouard.bingen@rdb.aphp.fr
Intitulé de l’équipe : CNR Streptocoque du groupe A chez l’enfant
Encadrement de master ou thèse non
BIDET PH., BRAHIMI N., CHALAS C., AUJARD Y., BINGEN E., Molecular characterization of serotype III group B streptococcus isolates causing neonatal meningitis J.Infect Dis. 2003 ; 188 : 1132-1137.
BONACORSI S, CLERMONT O, HOUDOUIN V, CORDEVANT C, BRAHIMI N, MARECAT A, TINSLEY C, NASSIF X, LANGE M, BINGEN E. Molecular Analysis and Experimental Virulence of French and North American Escherichia coli Neonatal Meningitis Isolates; Identification of a new Virulent Clone. J. Infect. Dis. 2003, 187, 1895-1906.
NEGRE V, BONACORSI S, SCHUBERT S, BIDET PH, NASSIF X, and BINGEN E. The siderophore receptor IroN but not the high-pathogenicity island or the hemin receptor ChuA, contributes to the bacteremic step of Escherichia coli neonatal meningitis.Infect Immun. 2004; 72 : 1216-1220.
HOUDOUIN V, DOIT C, MARIANI-KURKDJIAN P, BRAHIMI N, LOIRAT C, BOURRILLON A, BINGEN E. A pediatric cluster of Shigella dysenteriae serotype 1 diarrhea with Hemolytic Uremic Syndrome in two families from France. Clin Infect Dis. 2004 ; 38 : e96-9.
BIDET PH, BONACORSI S, CLERMONT O, DE MONTILLE C, BRAHIMI N, BINGEN E. Multiple insertional events, restricted by the genetic background, have led to PAI IIJ96-like domains acquisition among Escherichia coli strains of different clinical origins. Infect. Immun. 2005 ; 73 : 4081-4087.
BINGEN E, LEVY C, DE LA ROCQUE F, BOUCHERAT M, VARON E, ALONSO JM, DABERNAT H, REINERT PH, AUJARD Y, COHEN R and the Bacterial Meningitis Study Group. Bacterial Meningitis in Children ; a French Prospective Study. Clin Infect Dis. 2005 ; 41 : 1059-63.
BIDET P, MAHJOUB-MESSAI F, BLANCO J, BLANCO J, DEHEM M, AUJARD Y, BINGEN E and
S BONACORSI. Combined multilocus sequence typing and O serogrouping distinguishes Escherichia coli subtypes associated with infant urosepsis and or meningitis J. Infect. Dis 2007 ; 196 :297-303.
MAHJOUB-MESSAI F, DOIT C, KOECK JL, BILLARD T, EVRARD B, BIDET P, HUBANS C, RAYMOND J, LEVY C, COHEN R, BINGEN E. Population snapshot of Streptococcus pneumoniae serotype 19A isolates before and after the introduction of 7-valent pneumococcal vaccination in french children. J. Clin Microbiol 2009; 47: 837-840
PEIGNE C, BIDET P, MAHJOUB-MESSAI F, PLAINVERT C, BARBE V, MÉDIGUE C, FRAPY E, NASSIF X, DENAMUR E, BINGEN E, BONACORSI S. The plasmid of neonatal meningitis Escherichia coli strain S88 (O45:K1:H7) is closely related to avian pathogenic E. coli plasmids and is associated with high level bacteremia in neonatal rat meningitis model. Infect Immun. 2009; 77: 2272-2284.
BIDET P, LESTEVEN E, DOIT C, LIGUORI S, MARIANI-KURKDJIAN P, BONACORSI S, BINGEN E. Subtyping of emm1 group A streptococci causing invasive infections in France. J Clin Microbiol 2009;41:4146-9.
